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Groundbreaking research reveals that cancer cells exploit nerve pathways to suppress immune defenses. The study uncovers how the ATF4–SLIT2–CGRP axis triggers pain, weakens immunity, and reduces immunotherapy effectiveness — offering new hope for innovative cancer treatments.
New research reveals a dual-targeting approach that inhibits LOX and HSP70 — key drivers of extracellular matrix remodeling — to suppress melanoma metastasis and enhance immunotherapy response.